Impact of laparoscopic liver resection on bleeding complications in patients receiving antithrombotics

Table 1 Background characteristics of patients in the cohort n (%)

Variables	Total (n = 258)	ATT (n = 100)			Non-ATT (n = 158)
		LLR (n = 35)	OLR (n = 65)	P value	LLR (n = 42)	OLR (n = 116)	P value
Age, yr, median (range)	69 (36-89)	78 (59-90)	76 (52-92)	0.067	71 (45-89)	69 (36-86)	0.106
Gender				0.312			1
Female	80 (31.0)	10 (28.6)	12 (18.5)		15 (35.7)	43 (37.1)
Male	178 (69.0)	25 (71.4)	53 (81.6)		27 (64.3)	73 (62.9)
BMI				0.662			1
< 30 kg/m2	247 (95.7)	34 (97.1)	60 (92.3)		41 (97.6)	112 (96.6)
≥ 30 kg/m2	11 (4.3)	1 (2.9)	5 (7.7)		1 (2.4)	4 (3.4)
Performance status				0.124			1
0, 1	242 (93.8)	30 (85.7)	62 (95.4)		40 (95.2)	110 (94.8)
2, 3	16 (6.2)	5 (14.3)	3 (4.6)		2 (4.8)	6 (5.2)
Concurrent diseases
Diabetes mellitus	58 (22.5)	10 (28.6)	17 (26.2)	0.817	7 (16.7)	24 (20.7)	0.656
Hx of congestive heart failure	21 (8.1)	8 (22.9)	11 (16.9)	0.594	1 (2.4)	1 (0.9)	0.462
Coronary artery disease
Hx of PCI	49 (19.0)	17 (48.6)	31 (47.7)	1	1 (2.4)	0 (0.0)	0.266
Hx of CABG	7 (2.7)	4 (11.4)	3 (4.6)	0.236	0 (0.0)	0 (0.0)	-
Hx of cerebral infarction	26 (10.1)	5 (14.3)	17 (26.2)	0.212	0 (0.0)	4 (3.4)	0.574
Current hemo-/peritoneal dialysis	11 (4.3)	2 (5.7)	5 (7.7)	1	1 (2.4)	3 (2.6)	1
Anticoagulation therapy	30 (11.6)	8 (22.9)	22 (33.8)	0.360	-	-	-
Periop. heparin bridging	26 (10.1)	7 (20.0)	19 (29.2)	0.350	-	-	-
Preop. aspirin continuation	35 (13.6)	14 (40.0)	21 (32.3)	0.382	-	-	-

ATT: Antithrombotic therapy; LLR: Laparoscopic liver resection; OLR: Open liver resection; BMI: Body mass index; PCI: Percutaneous coronary intervention; CABG: Coronary artery bypass graft; periop.: Perioperative; preop.: Preoperative.