Retrospective Cohort Study
Copyright ©The Author(s) 2017.
World J Gastrointest Endosc. Aug 16, 2017; 9(8): 389-395
Published online Aug 16, 2017. doi: 10.4253/wjge.v9.i8.389
Table 2 Confocal laser endomicroscopy overall diagnostic accuracy with either confocal laser endomicroscopy target biopsy or surgical specimens as the Gold Standard n (%)
Biopsy/surgical specimen diagnosis
P value
Total (n = 144)Neoplastic lesions (n = 41)Non-neoplastic lesions (n = 103)
CLE diagnosis< 0.001
Neoplastic lesion48 (33.3)35 (85.4)13 (12.6)
Non-Neoplastic lesion96 (66.7)6 (14.6)90 (87.4)
CLE overall diagnostic accuracy
Sensitivity, n/T (%; 95%CI)35/41(85.37; 70.83-94.43)
Specificity, n/T (%; 95%CI)90/103(87.38; 79.38-93.11)
PPV, n/T (%; 95%CI)35/48(72.92; 61.46-81.97)
NPV, n/T (%; 95%CI)90/96(93.75; 87.71-96.93)
Observed agreement, n/T (%)125/144-86.81
Cohen’s Kappa, % (95%CI)69.2(56.50-81.90)