Does serotonin reuptake inhibitor therapy increase the risk of post-sphincterotomy bleeding in patients undergoing endoscopic retrograde cholangio-pancreatography?

Table 4 Patient demographics n (%)

Factor	Overall (n = 447)		SRI (n = 219)		No SRI (n = 228)		P value
	n	Summary	n	Summary	n	Summary
Age (yr)	445	64.4 ± 17.9	219	64.0 ± 16.8	226	64.7 ± 19.0	0.681
Male	447	112 (25.1)	219	47 (21.5)	228	65 (28.5)	0.0863
BMI	442	29.5 ± 7.5	218	29.7 ± 7.6	224	29.3 ± 7.4	0.591
Smoking	435	216 (49.7)	216	114 (52.8)	219	102 (46.6)	0.203
Alcohol use	432	161 (37.3)	215	69 (32.1)	217	92 (42.4)	0.0273
Cardiovascular disorder	447	111 (24.8)	219	53 (24.2)	228	58 (25.4)	0.763
Depression	445	160 (36.0)	219	99 (45.2)	226	61 (27.0)	< 0.0013
Renal disease	447	55 (12.3)	219	30 (13.7)	228	25 (11.0)	0.383
Intestinal disease	447	66 (14.8)	219	29 (13.2)	228	37 (16.2)	0.373
History of UGI bleed	389	1 (0.26)	207	0 (0.0)	182	1 (0.55)	0.474

¹ANOVA; ²Kruskal-Wallis test;

³Pearson's χ² test;

⁴Fisher's exact test. Intestinal diseases: Peptic ulcer, inflammatory bowel disease. Values presented as Mean ± SD or n (%). SRI: Serotonin reuptake inhibitor.