Does serotonin reuptake inhibitor therapy increase the risk of post-sphincterotomy bleeding in patients undergoing endoscopic retrograde cholangio-pancreatography?

Table 2 Bleeding grading system

Mild	Moderate	Severe
Transfusion is not required, with evidence of bleeding	Transfusion of 4 units or less is required	Transfusion of 5 units or more is required
Hemoglobin drop of less than 3 g/dL	No surgical intervention	Angiographic or surgical intervention
Immediate bleeding - seen in 30% patients (8) - endoscopic venous oozing which stopped with epinephrine
Delayed bleeding - occur up to 2 wk after the procedure - hematemesis, melena, haematochezia
Severe bleeding - 0.1%-0.5%

Adapt from Cotton et al[3].