Langerhans cell histiocytosis masquerading as acute appendicitis: Case report and review

Figure 1 Histology and immunohistochemical stains of appendix confirming diagnosis of Langerhans cell histiocytosis. The appendix shows an overgrowth of histiocytes in the lymphoid aggregates at 10 × (A) and 40 × (B) magnifications of H and E stains; while the electron microscopy images did not show Birbeck bodies due to previous fixation, the Langerin stain (CD207) demonstrates their presence in the areas of concern at 10 × (C) and 40 × (D) magnification. CD1a stains at 10 × (E) and 40 × (F); S-100 stains at 10 × (G) and 40 × (H).