Minireviews
Copyright ©The Author(s) 2016.
World J Gastrointest Endosc. Mar 10, 2016; 8(5): 267-272
Published online Mar 10, 2016. doi: 10.4253/wjge.v8.i5.267
Table 1 Summary of studies about premedication with pronase for visualization of the mucosa during conventional endoscopy
Ref.YearStudy designPremedication group (n)Mucosal visibility
Fujii et al[8]1998ProspectiveA: DMPS (34) B: DMPS + SB (32) C: DMPS + SB + pronase (34)C > A, B
Kuo et al[6]2002ProspectiveA: DMPS (34) B: DMPS + water (30) C: Pronase + water (31) D: Pronase + SB + water (32) E: Pronase + SB + DMPS + water (33)E > A, B, C, D
Chang et al[12]2007ProspectiveA: DMPS (39) B: DMPS + water (35) C: Pronase + SB + DMPS + water (34) D: N-acetylcystein + DMPS + water (39)C = D > A, B
Bhandari et al[30]2010ProspectiveA: Drinking of simethicone + pronase + water (35) B: Endoscopic flushing of simethicone + water (37) C: Endoscopic flushing of simethicone + pronase + water (40)A > B, C
Lee et al[13]2012ProspectiveA: DMPS + SB + pronase within 10 min (100) B: DMPS + SB within 10 min (100) C: DMPS + SB + pronase within 20 min (100) D: DMPS + SB within 20 min (100)A = C > B, D
Woo et al[26]2013ProspectiveA: Pronase + SB + DMPS within 10 min (98) B: Pronase + SB + DMPS between 10-30 min (97) C: Pronase + SB + DMPS at 30 min (99)A = B > C
Kim et al[7]2015ProspectiveA: Simethicone + SB + pronase (71) B: Simethicone (72)A > B