Gastric adenocarcinoma of fundic gland type: Endoscopic and clinicopathological features

Figure 2 Histological findings (hematoxylin and eosin staining): Case 1 (A, E, F), case 2 (B), case 3 (C) and case 4 (D). Well-differentiated adenocarcinomas with columnar cells that mimicked fundic gland cells were observed. Tumors histologically arose in the deeper zone of gastric mucosa (A-D). Irregularly anastomosing glandular structures with mildly enlarged and hyperchromatic nuclei were observed (E, F). Minimum carcinoma invasion of the submucosal layer was detected (C, D). Neither lymphatic nor vascular invasion was observed. Magnification: A-D (low-power view × 100), E (high-power view × 200), F (high-power view × 400).