Outcomes of submucosal (T1b) esophageal adenocarcinomas removed by endoscopic mucosal resection

Table 4 Studies evaluating endoscopic management of T1b esophageal adenocarcinoma

Ref.	# Patients	Depth of invasion	Histology	Margins	Remission	Recurrence	Survival
Manner et al[12]	21	sm1	Well to moderately differentiated, no lymphovascular invasion	Lateral margins negative in 12	95% at mean 5.3 mo	28% at mean 62 mo (range 45-89)	67% estimated 5-yr survival
Alvarez Herrero et al[14]	18	sm1 and sm2/3	Well, moderately and poorly differentiated, some with lymphovascular invasion	Not reported	Not reported	17%	Not reported
Tian et al[15]	29	sm1 and sm2-3	Not reported	Not reported	Not reported	Not reported	62% with median duration 34.8 mo
Manner et al[13]	66	sm1	Well to moderately differentiated, no lymphovascular invasion	Not reported	84% at mean 4.5 mo	21% at mean 22 mo (range 6-60)	84% estimated 5-yr survival