Endoscopic submucosal dissection of gastric tumors: A systematic review and meta-analysis

Table 4 Clinical outcomes among patients with gastric cancers who underwent endoscopic submucosal dissection

Outcomes	Studies, n	Tumor, n	Rate (95%CI)1
Efficacy measures
R0 resection	24	8520	87 (84-90)
Endoscopic en bloc resection	29	9652	94 (91-96)
Curative resection	10	5234	83 (80-86)
Safety measures
Immediate perforation2	31	12076	3.1 (2.4-3.9)
Immediate major bleeding2	6	303	2.9 (0.24-27)
Delayed perforation3	6	1486	0.15 (0.01-3.8)
Delayed bleeding3	29	11925	3.8 (3.0-4.7)
Recurrence (if R0)4	8	724	0.14 (0.004-4.6)
Recurrence (if not R0)4	7	152	8.5 (3.6-19)
Recurrence (irrespective of R0 status)4	18	7681	0.77 (0.39-1.5)

¹The rates are calculated as a percentage of the total number of tumors operated;

²Immediate refers to adverse outcomes occurring within 24 h of the procedure;

³Delayed refers to adverse outcome occurring 24 h after the procedure;

⁴Average follow-up was about 26, 24 and 37 mo for assessment of recurrence among tumors with R0, without R0, and irrespective of R0 status respectively. R0: Histologically-confirmed en bloc resection.