Bowel cleansing before colonoscopy: Balancing efficacy, safety, cost and patient tolerance

Table 1 Relative effectiveness and cost of available bowel preparations

Prep		% Adequate	Lesion detection rate	Cost1
4 L PEG	Single	51%-88%[16,64]	PDR 50.5%-51%[26,51]	PEG 3350 with electrolytes 4 L
	Split	71.3%-92.1%[23,51]	ADR 27.8-34.3%[51,70]	$26.59
2 L PEG	Single	83.5%-91%[45,64]	ADR 18.8%[70]	Moviprep 100 g/1 kit
	Split	74.4%-93.5%[45,48]		$91.55
MiraLAX	Single	67.8%-81.8%[29,31]	PDR 47%[26]	MiraLAX 8.3oz/238 g
	Split			$13.99
Sodium Phosphate		84.3%-90%[35,37]	Not Available	OsmoPrep 32 tabs
				$163.05
Sodium Picosulfate	Single	61.5%-82.6%[49,51]	PDR 38.5%-42.9%[51,53]	Prepopik, 2 pkts
	Split	81.6%-87.9%[49,50]	ADR 23.8%-31.3%[51,53]	$121.31
Oral Sulfate Solution	SuPrep	94.7%-98.4%[44,53]	PDR 50.9%[53]	SuPrep 1 kit
				$49.09
	Suclear	93.5%[45]	ADR 26%[53]	Suclear
				$76.38

¹Prices from RxPriceQuotes.com as listed for CVS w/exception of MiraLAX which was priced at local CVS. PEG: Polyethylene glycol; PDR: Polyp detection rate; ADR: Adenoma detection rate.