Current applications of endoscopic suturing

Table 3 Winthrop University Hospital endoscopic suturing registry

Indication	Number of Cases	Comment
POEM submucosal tunnel entry closures	100	100% successful closure Mean closure time: POEM/STER -10 min for a mean 2 cm defect EFTR/ESD -13 min for mean 3 cm defect Perforations/leaks-18 min for mean 1.8 cm defect Complications: No episodes of leakage or wound dehiscence 2 minor adverse events
EFTR of subepithelial tumor intentional defect closures	24
STER submucosal tunnel entry closures	6
ESD	22
Accidental perforation	16
Transoral outlet reduction	7	At mean 34 wk follow-up, mean 19.1 lb weight loss (2-34 lbs)
Primary sleeve gastroplasty	1	At 32 wk follow-up pt lost 40 lbs
Ulcer oversew	1	Required surgical intervention 2 wk post procedure due to lack of response
Leak/fistulae closure	14	2 leaks and 12 fistulas (9 gastric sleeves, 2 roux en y gastric bypass, 1 post- PEG tube removal. 2/2 (100%) leaks and 10/12 (83%) fistulas were successfully closed
Stent anchoring	10	Mean time was 8 min. No episodes of stent migration at mean 8 wk

POEM: Per oral endoscopic myotomy; EFTR: Endoscopic full thickness resection; STER: Submucosal tunnel endoscopic resection; ESD: Endoscopic submucosal dissection.