Feasibility and safety of endoscopic cryoablation at the duodenal papilla: Porcine model

Figure 3 High-power microscopic view (HE x 40 ) of porcine duodenal papilla 7 d after application of a liquid nitrogen cryospray dose of 20 secfor 4 freeze-thaw cycles. There is severe blunting and loss of villar tips, infiltration of fibrous tissue and influx of mixed inflammatory cells into the lamina propria and loss of crypt architecture extending through the mucosa. The submucosa and muscularis propria are intact.