Collagenous gastritis: Review

Table 1 Summary of 60 collagenous gastritis patients

Ref.	Age (yr)	Gender	Symptoms					Endoscopic Findings				H. pylori	Collagen band (μm)		Treatment	Follow-up biopsy duration (yr)	Histological changes	Clinical course
			Abdominal pain	Anemia	Diarrhea	Nausea, vomiting	Others	Nodularity	Erythema	Erosion, gastritis	Others		Stomach	Colon
[10]	7	F	+	+	-	-	-	-	-	+	-	NA	Yes	None	Oral iron supplementation, Proton-pump inhibitor	0.5	Improvement of inflammation remaining of collagen band	Improve
[11]	9	F	-	+	-	-	Retrosternal pain	-	+	-	-	-	13-96	< 5	Proton-pump inhibitor, Sucralfate, Steroid	1.1	No reduction	No change
[12]	9	F	+	-	-	-	-	-	-	+	-	-	35	None	Oral iron supplementation	4	Decrease of chronic gastritis, Unchanged collagen bands	Clinical remission
[13]	9	F	+	-	-	-	-	+	-	-	-	-	Yes	Yes	Oral iron supplementation	NA	NA	Improve
[14]	9	F	+	+	-	-	-	-	-	-	NA	NA	Yes	NA	Mesalazine		NA	Remain
[15]	12	F	-	-	-	+	-	+	-	-	-	+	NA	None	Proton-pump inhibitor	1	Severe erosive gastritis	Remain
[15]	12	F	+	-	-	-	-	+	-	-	-	+	NA	None	Proton-pump inhibitor	6	Decrease of nodules	Improve
[15]	12	F	+	-	-	-	-	+	-	-	-	+	NA	NA	Proton-pump inhibitor	0.17	NA	Improve
[16]	12	F	-	+	-	-	-	+	-	-	-	-	Yes	None	Oral iron supplementation	NA
[17]	13	F	-	+	-	-	-	+	-	-	-	-	76	NA	None	NA	NA	NA
[18]	14	F	+	-	-	-	-	+	-	-	-	-	75	None	Proton-pump inhibitor, Sucralfate, H2-receptor antagonist	12	Gradual progression	Remain
[17]	14	F	-	-	-	+	-	-	-	+	-	-	23	NA	Proton-pump inhibitor	NA	NA	Remain
[8]	15	F	+	+	-	-	Gastrointestinal bleeding	+	-	-	-	-	75	None	H2-receptor antagonist, sucralfate, furazolidone	2	No reduction	NA
[19]	15	F	-	+	-	-	-	+	-	-	-	+	NA	NA	Proton-pump inhibitors, Oral iron supplementation, Steroid	0.83	NA	Clinical remission
[17]	15	F	+	+	-	-	-	+	-	-	-	-	69	None	Steroid	3.4	Decrease of inflammation	Improve
[4]	16	F	+	+	-	-	-	+	-	-	-	-	NA	None	H2-receptor antagonist, Proton-pump inhibitor, Oral iron supplementation,	6	No reduction	Improvement of anemia
[20]	20	F	+	-	-	-	-	+	-	-	-	-	30-70	None	Proton-pump inhibitor	2	No change	NA
[21]	22	F	-	+	-	-	-	+	-	-	-	-	40-45	NA	None	NA	NA	NA
[40]	22	F	+	+	-	-	Gastrointestinal bleeding	+	-	+	Duodenitis	-	60-100	None	H2-receptor antagonist,Proton-pump inhibitor	1	No change	Improve
[22]	25	F	-	+	-	-	-	+	-	-	-	-	24	Yes	None	0.25	No change	NA
[23]	25	F	-	-	+	-	-	-	-	-	NA	NA	Yes	NA	None	NA	NA	NA
[23]	25	F	-	-	+	-	Body weight loss	-	-	-	NA	NA	Yes	Yes	NA	NA	NA	NA
[39]	25	F	+	+	-	-	-	+	-	-	NA	-	17	None	H2-receptor antagonist,Proton-pump inhibitor	4	No change	No change
[24]	35	F	-	-	+	-	Abdominal distention	+	-	-	-	-	20-30	None	Sulfasalazine	NA	NA	Remission of diarrhea
[4]	39	F	-	+	-	-	Fatigue	-	-	-	Normal	-	NA	Yes	Gluten-free diet	4	No reduction	Improve
[21]	40	F	-	-	+	-	-	-	-	-	Normal	-	40-41	None	Steroid, Sulfasalazine, Parenteral nutrition	2	Resolve of collagen band	NA
[21]	52	F	-	+	-	-	-	-	-	-	Normal	+	15-20	None	None	NA	NA	NA
[17]	52	F	+	-	+	-	-	-	-	+	-	-	78	None	Gluten-free diet	NA	NA	Improve
[25]	57	F	-	-	+	-	-	-	+	-	-	-	20-40	> 30	Steroid	1.5	No change	Responded to steroid
[17]	57	F	+	-	-	-	-	+	-	-	-	-	40	NA	Gluten-free diet	NA	NA	Improve
[22]	58	F	-	-	+	-	-	+	-	-	-	-	15.8	None	Steroid	1.5	Improvement of inflammation remaining of collagen band	NA
[17]	62	F	-	-	-	+	-	-	-	+	-	-	94	NA	None	NA	NA	NA
[2]	68	F	-	+	-	-	Dyspepsia	+	-	-	-	-	None	None	Oral iron supplementation, Proton-pump inhibitor	0.83	Improvement of inflammation increase of collagen band	Partial relief
[26]	74	F	+	-	+	-	-	-	+	-	-	-	Yes	Yes	Proton-pump inhibitor	0.08	No change	Improve
[27]	75	F	-	-	+	-	-	-	-	-	Normal	NA	30-60	10-30	NA	NA	NA	NA
[28]	0.75	M	-	-	+	-	-	-	-	+	-	+	50	17	Steroid, Total parenteral nutrition	14	Gradual progression	Improve with total parenteral nutrition
[29]	2	M	-	-	+	-	-	-	-	+	-	+	> 5	NA	Proton-pump inhibitors, Mesalazine, Steroid, Bismuth subsalicylate	NA	NA	Improve
[30]	9	M	+	+	-	-	-	+	-	-	-	-	30-150	None	Oral iron supplementation	2	NA	NA
[21]	11	M	-	+	-	-	-	+	-	-	-	-	50-69	None	None	8	Moderate decrease	NA
[10]	11	M	+	+	-	-	-	+	-	-	-	NA	> 10	NA	Proton-pump inhibitor, Oral iron supplementation	5	Improvement of inflammationresolve of collagen band	Improve
[13]	15	M	-	-	+	-	-	+	-	-	-	-	30	30	Proton-pump inhibitor, Steroid, Mesalazine	NA	NA	Clinical remission
[17]	19	M	+	+	-	-	Perforation of ulcer	+	-	-	-	-	40	NA	Sucralfate	0.25	Improvement of inflammationdecrease of collagen band	Improve
[38]	19	M	+	-	-	-	Constipation	+	-	-	-	NA	15	None	None	0.5	Progression	Improve
[31]	20	M	+	-	-	+	-	+	-	-	-	-	15-43	20-30	H2-receptor antagonist, Oral iron supplementation	4	Progression	No change
[32]	25	M	+	-	-	+	Abdominal distention	+	-	-	-	-	> 10	None	Proton-pump inhibitor	NA	NA	Improve
[33]	25	M	+	-	-	-	-	-	-	-	Normal	+	Yes	NA	None	NA	NA	NA
[17]	34	M	+	+	-	-	Gastrointestinal bleeding	+	-	-	-	-	78	NA	None	9.9	Gradual progression	NA
[33]	35	M	-	-	-	-	-	+	-	-	-	-	50	None	None	14	Increase	Increase
[21]	36	M	NA	NA	NA	NA	NA	-	-	-	NA	-	15-20	NA	None	NA	NA	NA
[35]	37	M	-	-	+	-	Body weight loss	+	-	-	-	-	120	None	Steroid, Azathioprine, Parenteral nutrition	1.67	No change	Improve
[36]	42	M	-	+	+	-	Abdominal distention, Rectal bleeding	-	+	-	-	NA	26-10	None	Gluten-free diet	0.25	No change	Improve
[9]	47	M	+	-	-	-	-	-	-	-	Normal	+	70	None	Proton-pump inhibitor	NA	NA	Improve
[17]	56	M	-	-	-	+	-	+	-	-	-	-	87	None	Steroid, Gluten-free diet	NA	NA	Improve
[3]	56	M	+	-	-	+	Body weight loss	-	-	+	-	NA	Yes	NA	NA	NA	NA	NA
[37]	57	M	-	+	+	-	-	-	+	-	-	NA	13-45	None	Steroid, Mesalazine	NA	NA	Improve
[17]	59	M	-	-	-	-	Dysphagia	-	-	-	Normal	-	54	NA	None	NA	NA	NA
[17]	68	M	-	-	+	-	-	-	-	+	-	-	20	NA	Steroid, Gluten-free diet	0.75	Gradual progression	Remain
[23]	72	M	-	-	+	-	Body weight loss	-	-	-	NA	NA	Yes	Yes	Steroid	NA	NA	Improve
[21]	77	M	-	-	-	-	-	-	-	+	-	+	20-28	NA	None	NA	NA	NA
[17]	80	M	-	+	+	-	-	+	-	-	-	-	47	None	Steroid	NA	NA	NA

NA: Not available.