Endosonography in the diagnosis and management of pancreatic cysts

doi:10.4253/wjge.v7.i3.213

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Endosc. Mar 16, 2015; 7(3): 213-223
Published online Mar 16, 2015. doi: 10.4253/wjge.v7.i3.213

Table 3 Endoscopic ultrasound-fine needle aspiration cyst fluid analysis

Cyst fluid marker	Type of cyst	Sensitivity	Specificity
CEA < 5 ng/mL	SCA, pseudocyst, neuroendocrine tumor	54%	94%
CEA >192 ng/mL	Mucinous cyst (MCN or IPMN)	73%	84%
CEA > 800 ng/mL	Mucinous cyst (MCN or IPMN)	98%	48%
Amylase < 250 U/L	Excludes pseudocyst	44%	98%
KRAS mutation + LOH	Malignant cyst	37%	96%
KRAS mutation	Mucinous cyst (MCN or IPMN)	54%	100%

CEA: Carcinoembryonic antigen; SCA: Serous cystadenoma; MCN: Mucinous cystic neoplasm; IPMN: Intraductal papillary mucinous neoplasm; LOH: Loss of heterozygosity.

Citation: Kadiyala V, Lee LS. Endosonography in the diagnosis and management of pancreatic cysts. World J Gastrointest Endosc 2015; 7(3): 213-223
URL: https://www.wjgnet.com/1948-5190/full/v7/i3/213.htm
DOI: https://dx.doi.org/10.4253/wjge.v7.i3.213