Small bowel capsule endoscopy: Where are we after almost 15 years of use?

Figure 3 Recommended approaches for diagnosis and treatment of obscure gastrointestinal bleeding. ¹DBE is recommended in (1) patients requiring a biopsy or a therapeutic intervention (2) patients with an initial negative CE and suspicion of a small bowel lesion (3) large scale hospitals or (4) hospitals where CE is not available; ²If a lesion is suspected, further work-up is needed; ³Rebleeding was defined as a change from occult to overt bleeding or a hemoglobin level drop more than 4 g/dL. DBE: Double balloon enteroscopy; PE: Push enteroscopy; IOE: Intraoperative enteroscopy; Routine endoscopy: Uni/bidirectional endoscopy.