Lymphoepithelioma-like esophageal carcinoma with macroscopic reduction

Figure 4 The histopathological findings. A: Poorly differentiated squamous cells and lymphocytes that had infiltrated into the carcinoma cell nests were observed (HE staining, original magnification × 400); B: Prominent infiltration of cytotoxic T lymphoid cells that stained positive for CD8 was observed between and around the carcinoma cells (× 400); C: Strong expression of human leukocyte antigen-DR was evident in the cell membrane in nearly all carcinoma cells and in the lymphocytes around the tumor (× 400).