Laparoscopic management of gastric gastrointestinal stromal tumors

Table 1 Non-comparative series of laparoscopic resection of gastric gastrointestinal stromal tumor

Ref.	n	Age (yr)	Tumor size	Tumor localization	Type of surgery	OR time (min)	Notes	Complications/ conversions	Follow-up (mo)
Privette et al[25]	12	60.5	5.2 cm PG 4.6 cm TransG 5.5 cm DG	5 Fundus or greater curvature 3 Prepyloric or antral 5 Lesser curvature	5 PG × Lap 3 DG × Lap 5 TransG × Lap	PG 180 (122-262) DG: 322 (256-340) TransG: 236 (202-265)	9/12 GIST 1 Schwannoma 2 Leiomiomas LOS: GP: 3.4 GD: 8.3 GT: 3.3	16.6% complication 1 Enterotomy 1 GI Bleeding No conversions	Only specified for 5 pts
Sexton et al[32]	61	59.1 ± 19	3.8 ± 1.8 AR: 229.7 NAR 140.9	Fundus 19 Antrum 18 Body 17 GE junction 7 Pylorus 2	PG 52 DG 4 TotGas 3 TransG 3	151.9 ± 67.3	LOS: 3.9 ±2 LOS AR: 3.9, NAR: 4.1	16.4% complication No conversions 1 POP death	15 (0-103) 3 recurrences
Berindoague et al[9]	22	66.7	5.6 (2.5-12.5)	Upper third 6 Middle third 7 Lower third 10	GP 13 1 LAP-HA TotGas 1 LAP TotGast 1 LAP-HA GD 1 TransG	NR	18/22 GIST 1 Adenomyoma 1 Hamartoma 1 Plasmocytoma 1 Parasitic Tumor (anisakis) LOS 6 (4-32)	18.2% complication 3 Delayed gastric emptying 1 Intestinal Obstruction 2 Conversions (9.1%)	32 m (1-72) 1 recurrence
De Vogelaere et al[24]	31	63.8	4.4 (0.4-11)	Anterior gastric wall 23 Others not specified	31 PG	99	LOS 8.5	3.2% Complication 1 POP Bleeding	56.3 No recurrences
Hwang et al[10]	63	52.8	3.5 GE Junction 3.4 Prepyloric Size of other tumor not specified	7 GE junction Upper third 22 Middle third 11 Lower third 19 4 Prepyloric	3 DG 37 PG 23 TransG (5 Enucleations)	86.1 ± 43.7	LOS 5.3 ± 1 1.8 41 GIST 8 Leiomyoma 4 Carcinoids 1 Liposarcoma 6 Heterotopic Pancreas 2 Hyperplastic Polyps 1 Parasitic Infection	4.7% Complication 1 Staple line bleeding 1 SSI 1 Staple line dehiscence	14.9 (2-42) No recurrences
Novitsky et al[26]	50	60 ± 13	4.4 ± 2.0 cm	GE Junction 8 Cardias 9 Anterior Wall 10 Posterior Wall 4 Greater Curvature 6 Lesser Curvature 3 Antrum 4 Prepyloric 6	TotGas 1 DG 2 PG 40 LAP/END 4 LAP-HA 3	135 ± 56	LOS 3.8 ± 1.6	8% 4 Minor complications	36 (4-84) 4 recurrences
Lai et al[2]	28	56.9 ± 12.4	3.4 ± 1.6	Upper third 13 Middle third 8 Lower third 7	28 PG	189.6 ± 79.5 Stapled 194.3 ± 50.5 Hand-Sewn	LOS 6.7 ± 1.8	3.5% conversion	43.3 ± 23.5 No recurrences
Choi et al[36]	23	59.7 ± 8.3	4.2 ±2.1	Upper third 13 Middle third 5 Lower third 5	23 PG	104.3	LOS 5.2 ± 2.3	4.3% complication 1 Delayed gastric emptying No conversions	61 (7-98)
Nguyen et al[22]	28	65	4.6 (0.4-11.5)	LAP PG 22 Subtotal Gastrectomy 3 OS (Converted) : TotGas 1 Intraluminal excision 1 1 Not specified	23 GP × LAP 3 GD × LAP 1 GT × LAP 1 TotGas × CA (converted)	143 (46-336) This includes Small Bowel GIST resections. No data only on gastric resections	LOS 4 (1-50 d)	9% complications 11% 3 conversions Mortality 1 POP death This includes Small Bowel GIST resections. No data only on gastric resections	NS
Huguet et al[37]	33	68	3.9 (0.5-10.5),	GE Junction 5 Body 24 Antrum 4	PG 29 LAP-HA PG 4	124 (30-253)	LOS 3 (1-40)	9% complications 2 POP Bleeding 1 SSI 6% conversions	13 (3-64) No recurrences
Ronellenfitsch et al[38]	17	56 (43-79)	2.9 (0.8-6)	11 Not specified 6 Antrum	17 PG	130 (80-201)	LOS 7 (5-95)	11.8% Complications: Staple leaks 5% conversion (peritoneal adhesions)	18 (1-53) No recurrences
Tagaya et al[39]	15	65.3 (52-75 years)	TransG 2.9 (1.7-6.5) GP 3.9 (1.2-8)	TransG: Upper third 4 Middle third 1 Lower third 1 PG: Greater curvature 2 Lesser curvature 1 Anterior wall 2 Middle third Ant wall 1 Middle Third Post wall 1	TransG 8 PG 7	TransG:168 (132-211) PG: 121 (60-190)	LOS TransG: 8.8 ( 7-12) LOS PG: 9.6 (7-14)	No complications	After final Pathology only 9 tumors were GIST TransG 18-73 PG: 6-122 No recurrences

GLA: Gasless laparoscopy-assisted; PG: Wedge Resection or Partial Gastrectomy; DG: Distal Gastrectomy; TransG: Transgastric Gastrectomies; TotGas: Total Gastrectomy; OS: Open surgery; AR: Anatomic resections; NAR: Non-anatomic resections; LOS: Length of stay; NS: Not specified; LAP/END: Laparoendoscopic resection; LAP-HA: Laparoscopic hand-assisted; RG: Remnant Gastrectomy; Prox Gas: Proximal Gastrectomy; SSI: Surgical site infection.