Preoperative biliary drainage in hilar cholangiocarcinoma: When and how?

Table 1 Studies which have analyzed preoperative biliary drainage in hilar cholangiocarcinoma patients undergoing surgical resection

Ref.	Total number of patients with PBD	PBD-associated morbidity	Serum bilirubin before surgery (mg/dL)	Duration of PBD (d)	Postoperative morbidity	Postoperative complications	Infectious complications	5-year survival rate
Hochwald et al[9], 19991	42 (PTBD 23; ERBD 13; intraoperative 3; ENBD 1; PTBD and ERBD 1; ERBD and ENBD 1)	-	5.6 ± 0.9	-	90%	5%	52%	-
Figueras et al[10], 20001	11 (PTBD 11)	-	11.0 ± 9.4	16 ± 10	100%	9%	18%	25%
Ferrero et al[11], 20091	30 (PTBD 18; ERBD 7; ERBD and PTBD 3; intraoperative 2)	23%	3.1 (0.3-14.1)	27.5 (10-90)	70%	3%	11%	-
Kloek et al[12], 20101	101 (PTBD 11; ERBD 90)	76%	PTBD 1.1 ± 0.8; ERBD 1.3 ± 1.2	PTBD 11 (3-21); ERBD 15 (4-29)	-	-	48%	-
Grandadam et al[13], 20101	12 (PTBD 12)	25%	4.1 ± 2.5	32 ± 9	13%	0	-	42%
Kawakami et al[14], 20111	128 (PTBD 48; ERBD 20; ENBD 60)	Total 40% (PTBD 31%; ERBD 65%; ENBD 38%)	10.5 (2.2-29.3)	11.4 (1-154)	13%	3%	-	-
Ratti et al[15], 20131	55 (PTBD 51; ERBD 4)	18%	3.4 ± 1.5	24 (10-36)	46%	5%	7%	29%
Farges et al[8], 20131	180 (PTBD 104; ERBD 63; PTBD and ERBD 13)	33%	2.8 (1.2-5.6)	32	68%	9%	-	-

¹All reports were retrospective studies. Data are expressed as mean ± SD or median (range). PBD: Preoperative biliary drainage; PTBD: Percutaneous transhepatic biliary drainage; ERBD: Endoscopic retrograde biliary drainage; ENBD: Endoscopic nasobiliary drainage.