Clinical outcomes and risk factors for perforation in gastric endoscopic submucosal dissection: A prospective pilot study

Table 3 Subgroup analysis: Comparison in various factors between perforation and silent free air

	Perforation (n = 8)	Silent free air on CT (n = 35)	P value
Tumor-related factors
Location: Upper/middle/ lower	2/6/0	9/21/5	NS
Scar: Positive/negative	0/6	5/30	NS
Depth of invasion: M/SM and beyond	5/3	5/30	NS
Treatment-related factors
Operator: Experienced/ less-experienced	2/6	16/19	NS
Resected dimensions (cm2)	24.0 ± 24.9	10.4 ± 7.2	NS
Procedure time (min)	203.1 ± 114.3	145.1 ± 76.5	NS
Clinical parameters
Body temperature	37.3 ± 0.6	36.8 ± 0.6	0.04
White blood cell (/mm3)	9898.8 ± 3149.4	10658.0 ± 3119.3	NS
C-reactive protein (mg/dL)	2.4 ± 1.3	1.4 ± 1.0	0.03
Oral intake (d)	3.0	4.0 ± 1.5	NS
Hospital stay (d)	10.9 ± 1.5	10.7 ± 2.1	NS

Data are expressed as mean ± SD. CT: Computed tomography; M: Intramucosal cancer and adenoma; SM: Submucosal invasive cancer; NS: Not significant.