Usefulness of applying lidocaine in esophagogastroduodenoscopy performed under sedation with propofol

Table 2 Influence of lidocaine on propofol dose

	Lidocaine	Placebo	Diff1	P
Average BIS	68.1 ± 7.5	68.8 ± 7.6	0.76 (-2.0, 3.5)	0.58
Total examination values
Total examination time, s	405.0 ± 134.8	387.0 ± 127.6	18.6 (-29.0, 66.2)	0.44
Total propofol dose, mg	134.9 ± 42.5	129.2 ± 40.4	5.6 (-9.4, 20.7)	0.45
Total propofol dose adjusted weight and time, mg/kg per minute	310.7 ± 139.2	280.1 ± 87.7	30.6 (-11.5, 72.7)	0.15
Intraprocedural examination values2
Partial examination time, s	281.8 ± 137.3	265.5 ± 122.3	16.3 (-30.8, 63.5)	0.49
Partial propofol dose, mg	40.9 ± 33.7	38.9 ± 31.4	2 (-9.7, 13.8)	0.73
Partial propofol dose adjusted weight and time, mg/kg per minute	135.3 ± 151.7	122.7 ± 96.5	12.6 (-33.5, 58.7)	0.58

¹Differences are expressed as RR with their respective absolute values;

²Measurements recorded from the time of endoscope insertion into the oral cavity up to the time of withdrawal, excluding the time of anaesthetic induction. Quantitative and qualitative variables are expressed as average ± standard deviation and as percentage with 95%CI, respectively. BIS: Bispectral index.