Image-enhanced endoscopy for diagnosis of colorectal tumors in view of endoscopic treatment

Table 3 Reports about image-enhanced endoscopy with magnification for differentiation of massively submocosal invasive cancer (%)

Ref.	System	No. of cases	Accuracy	Sensitivity	Specificity	PPV	NPV
Fukuzawa et al[39]	NBI	112	92.9	81.4	100.0	100.0	90.0
Wada et al[35]	NBI	584	96.1	100.0	95.8	-	-
Tanaka et al[17]	NBI	97	94.1	63.8	100.0	-	-
Ikematsu et al[58]	NBI	130	87.7	84.8	88.7	71.8	94.5
Yoshida et al[22]	FICE	124	98.3	77.7	100.0	100.0	98.2

NBI: Narrow-band imaging; FICE: Flexible spectral imaging color enhancement; PPV: Positive predictive value; NPV: Negative predictive value.