Transnasal and standard transoral endoscopies in the screening of gastric mucosal neoplasias

doi:10.4253/wjge.v3.i8.162

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Endosc. Aug 16, 2011; 3(8): 162-170
Published online Aug 16, 2011. doi: 10.4253/wjge.v3.i8.162

Table 2 Screening performance of the two esophagogastroduodenoscopies in subjects with or without Helicobacter pylori infection (mean ± SD) n (%)

	Total subjects (H. pylori analyzed)	H. pylori
	Total subjects (H. pylori analyzed)	Positive	Negative
Screened by transnasal EGD
Screened subjects	1280	510	770
Age (yr)	53.4 ± 15.4	56.8 ± 13.6^c	50.2 ± 14.3
Males	623 (48.7)^a	268 (52.5)^a	355 (46.1)^a
Smokers	247 (19.3)	118 (23.1)^c	129 (16.7)^a
Subjects with gastric neoplasia/DR	21/0.0164	16/0.0314^c	5/0.00649
Location of neoplasia (U/M/L)	7/6/8	4/6/6	3/0/2
Adenoma cases/DR	3/0.0023	3/0.00589	0/0
Size of adenoma (mm)	9.7 ± 4.0	9.7 ± 4.0	0
Cancer cases/DR	18/0.0141	13/0.0255^c	5/0.00649
Size of cancer (mm)	31.2 ± 19.5	25.5 ± 13.3	46.0 ± 28.2
Morphological cancer type (I-IIa/IIb/IIc-III/Ad)	6/1/4/7	5/0/4/4	1/1/0/3
With intestinal-type cancer	16 (88.9)	12 (92.3)	4 (80)
Depth of invasion (m/sm/pm-)	5/6/7	4/5/4	1/1/3
With early cancer	12 (66.7)	10 (76.9)	2 (40)
Screened by transoral EGD
Screened subjects	1707	692	1015
Age (yr)	53.5 ± 15.4	56.3 ± 14.7^c	51.8 ± 14.8
Males	655 (38.4)	298 (43.1)	357 (35.2)
Smokers	354 (20.7)	141 (20.3)	213 (21.0)
Subjects with gastric neoplasia/DR	33/0.0193	26/0.0376^c	6/0.00591
Location of neoplasia (U/M/L)	12/8/12	10/8/9	2/0/3
Adenoma cases/DR	9/0.0052	5/0.00722	4/0.00394
Size of adenoma (mm)	10.8 ± 7.9	13 ± 11.5	10 ± 4.08
Cancer cases/DR	23/0.0135	21/0.0303^c	2/0.00197
Size of cancer (mm)	22.3 ± 12.8	23.2 ± 13.4	20 ± 0
Morphological cancer type (I-IIa/IIb/IIc-III/Ad)	6/0/12/5	6/0/10/5	0/0/2/0
With intestinal-type cancer	15 (65.2)	14 (66.7)	1 (50)
Depth of invasion (m/sm/pm-)	15/3/5	13/3/5	2/0/0
With early cancer	18 (78.3)	14 (76.2)	2 (100)

^aP < 0.05 vs transoral,

^cP < 0.05 vs Helicobacter pylori (H. pylori)-negative. DR: Detection rate; U: Upper third of the stomach; M: Middle third of the stomach; L: Lower third of the stomach; EGD: Esophagogastroduodenoscopy.

Citation: Nakata H, Enomoto S, Maekita T, Inoue I, Ueda K, Deguchi H, Shingaki N, Moribata K, Maeda Y, Mori Y, Iguchi M, Tamai H, Yamamichi N, Fujishiro M, Kato J, Ichinose M. Transnasal and standard transoral endoscopies in the screening of gastric mucosal neoplasias. World J Gastrointest Endosc 2011; 3(8): 162-170
URL: https://www.wjgnet.com/1948-5190/full/v3/i8/162.htm
DOI: https://dx.doi.org/10.4253/wjge.v3.i8.162