Gastrointestinal stromal tumor of the stomach: How to manage?

Figure 3 Management process of gastric submucosal tumor (in a case of gastrointestinal stromal tumor) according to our institutional algorithm (Figure 1). Quoted and modified from reference [15]. A: Esophagogastroduodenoscopy (EGD) shows submucosal tumor in the lower body of the stomach; B: Endoscopic ultrasound (EUS) reveals 2.5 cm subepithelial hypoechoic solid tumor with continuity to proper muscle layer (arrow-mp); C: Puncture of the small gastrointestinal stromal tumor (GIST) under EUS guidance. Arrow: tip of needle; D: The immunohistochemical fnding of endoscopic ultrasound-guided fne needle aspiration (EUS-FNA) specimen of GIST. The tumor is diffusely positive for c-kit.