Prospective randomized study comparing Franseen 22-gauge vs standard 22-gauge needle for endoscopic ultrasound guided sampling of pancreatic solid lesions

doi:10.4253/wjge.v17.i4.101998

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Apr 16, 2025 (publication date) through Apr 21, 2025

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Clinical Trial

World J Gastrointest Endosc. Apr 16, 2025; 17(4): 101998
Published online Apr 16, 2025. doi: 10.4253/wjge.v17.i4.101998

Table 5 Comparison of the diagnostic performance of standard (fine needle aspiration) and Franseen (fine needle biopsy) needles

Metrics	FNA	FNB	Statistical difference	P value¹
Sensitivity	0.809	0.915	5.000	0.025
Specificity	0.667	0.667	-	-
PPV	0.974	0.977	0.913	0.361
NPV	0.182	0.333	2.202	0.028
Accuracy	0.800	0.900	3.200	0.074

¹McNemar (for sensitivity and specificity comparisons), Moskowitz and Pepe (for positive predictive value and negative predictive value comparisons) tests.

FNA: Fine needle aspiration; FNB: Fine needle biopsy; PPV: Positive predictive value; NPV: Negative predictive value.

Citation: Paduani GF, Felipe LM, De Paulo GA, Lenz L, Martins BC, Matuguma SE, Safatle-Ribeiro AV, De Mello ES, Maluf-Filho F. Prospective randomized study comparing Franseen 22-gauge vs standard 22-gauge needle for endoscopic ultrasound guided sampling of pancreatic solid lesions. World J Gastrointest Endosc 2025; 17(4): 101998
URL: https://www.wjgnet.com/1948-5190/full/v17/i4/101998.htm
DOI: https://dx.doi.org/10.4253/wjge.v17.i4.101998