Comparison of endoscopic submucosal dissection and transanal endoscopic microsurgery for stage 1 rectal neuroendocrine tumors

Table 3 Outcomes between endoscopic submucosal dissection and transanal endoscopic microsurgery groups according to lesion size, n (%)

Variables	< 10 mm (n = 84)			10-20 mm (n = 44)
	ESD (n = 56)	TEM (n = 28)	P value	ESD (n = 28)	TEM (n = 16)	P value
Lesion size, mm, median (IQR)	6.0 (5.0-8.0)	5.0 (4.5-8.0)	0.101	10.0 (10.0-12.0)	11.0 (10.0-15.0)	0.277
Age, year, mean ± SD	44.8 ± 14.1	44.3 ± 11.9	0.872	44.4 ± 12.4	47.1 ± 12.9	0.513
Follow-up time, month, median (IQR)	24.5 (12.5-36.0)	23.0 (15.0-38.0)	0.962	35.0 (20.0-54.0)	30.0 (22.5-48.0)	0.798
Hospital day, day, median (IQR)	6.0 (5.0-7.0)	9.0 (7.0-11.5)	< 0.001	6.0 (5.0-7.0)	9.0 (7.0-13.0)	< 0.001
Cost, kilo-CNY, median (IQR)	10.8 (9.5-12.2)	22.4 (18.3-26.7)	< 0.001	11.5 (10.2-12.6)	20.0 (16.9-24.8)	< 0.001
Adverse event	1 (1.8)	1 (3.6)	1.000	2 (7.1)	1 (6.3)	1.000
En bloc resection	56 (100.0)	28 (100.0)	/	23 (100.0)	16 (100.0)	/
R0 resection	50 (89.3)	27 (96.4)	0.416	23 (82.1)	16 (100.0)	0.141
Recurrence	0 (0.0)	0 (0.0)	/	0 (0.0)	1 (6.3)	0.364

ESD: Endoscopic submucosal dissection; TEM: Transanal endoscopic microsurgery; IQR: Interquartile range; CNY: China Yuan.