Discordance between endoscopic and histopathologic assessment in ileal Crohn’s disease

doi:10.4253/wjge.v17.i2.101284

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Feb 16, 2025 (publication date) through Feb 13, 2025

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Endosc. Feb 16, 2025; 17(2): 101284
Published online Feb 16, 2025. doi: 10.4253/wjge.v17.i2.101284

Table 2 Relationship between ileal simple endoscopic score in Crohn’s disease (ileal Simple Endoscopic Score for Crohn's Disease) and histologic indices, n (%)/mean ± SD

	Ileal SESCD 0 (n = 12)	Ileal SESCD 3 (n = 4)	Ileal SESCD ≥ 4 (n = 20)
Ulcer subscore¹	0	0	8 (40)
Active (neutrophilic) histologic inflammation²	0	0	16 (80)
Chronic (lymphoplasmacytic) histologic inflammation³	0	0	11 (55)
RHI	0.3 ± 0.5	0.3 ± 0.5	13.3 ± 10.4
GHAS	0.6 ± 1.2	1.0 ± 2.0	7.6 ± 4.6
PHRI	0	0	2.3 ± 1.5

¹Ulcer subscore (= 1 on Global Histology Activity Score and > 1 on Robarts Histopathology Index ulcer/erosion subscore).

²Active inflammation (Robarts Histopathology Index > 3).

³Chronic inflammation (Robarts Histopathology Index subscore of mononuclear cell infiltration > 1).

GHAS: Global Histology Activity Score; RHI: Robarts Histopathology Index; PHRI: Picasso Histological Remission Index.

Citation: Lee SD, Mau B, Avalos CJ, Clark-Snustad KD, Kamp KJ, Gui X. Discordance between endoscopic and histopathologic assessment in ileal Crohn’s disease. World J Gastrointest Endosc 2025; 17(2): 101284
URL: https://www.wjgnet.com/1948-5190/full/v17/i2/101284.htm
DOI: https://dx.doi.org/10.4253/wjge.v17.i2.101284