Leucine-rich alpha-2 glycoprotein as a superior biomarker to C-reactive protein for detecting small bowel lesions in Crohn’s disease

Figure 6 Changes in each parameter in patients who underwent follow-up balloon-assisted enteroscopy. ^aP < 0.05, ^bP < 0.01. Patients who improved the Modified simple endoscopic score for Crohn’s disease (mSES-CD) in the ileum had significantly lower leucine-rich alpha-2 glycoprotein, C-reactive protein, and albumin levels, whereas these parameters did not show significant differences in patients whose simple endoscopic score for Crohn’s disease remained unchanged. The Harvey-Bradshaw index consistently showed no significant differences. A: Patients with at least one point of improvement in the mSES-CD in the ileum (n = 16); B: Patients with unchanged mSES-CD in the ileum (n = 19). LRG: Leucine-rich alpha-2 glycoprotein; CRP: C-reactive protein; HBI: Harvey-Bradshaw index.