Leucine-rich alpha-2 glycoprotein as a superior biomarker to C-reactive protein for detecting small bowel lesions in Crohn’s disease

Table 4 Area under curves, cut-off value, sensitivity, and specificity of leucine-rich alpha-2 glycoprotein in predicting endoscopic healing in the small intestine determined using balloon-assisted enteroscopy according to the previous and present studies

Ref.	Number of patients	AUC (95%CI)	Cut-off value	Sensitivity	Specificity
Kawamoto et al[25]	108	0.850 (0.766-0.933)	13.4 μg/mL	0.79	0.82
Kawamoto et al[26]	75	0.805 (0.703-0.907)	13 μg/mL	0.71	0.80
Kawamura et al[27]	36	0.885 (0.744-1.000)	8.9 μg/mL	0.926	0.778
Present study	104	0.809 (0.724-0.894)	12.4 μg/mL	0.767	0.787

AUC: Area under the curve; CI: Confidence interval.