Effect of etomidate added to propofol target-controlled infusion in bidirectional endoscopy: A randomized clinical trial

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Feb 16, 2025 (publication date) through Feb 13, 2025

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Clinical Trial

World J Gastrointest Endosc. Feb 16, 2025; 17(2): 100722
Published online Feb 16, 2025. doi: 10.4253/wjge.v17.i2.100722

Table 2 Comparison of adverse events in three groups, n (%)

	P group	0.1EP group	0.15EP group	P value
Hypotension	48 (36.4)	32 (29.1)^a	13 (11.8)^b^,^c	< 0.001
Bradycardia Respiratory depression	27 (24.5)	15 (13.6)^a	9 (8.2)^b	0.002
Slight	34 (30.9)	18 (16.3)^a	12 (10.9)^b	0.001
Severe	17 (15.5)	11 (10.0)	5 (4.5)^b	0.026
Injection pain				< 0.001
0 score	54 (49.1)	73 (66.4)^a	89 (80.1)^b^,^c
1 score	33 (30.0)	28 (25.5)	19 (17.3)^b
2 score	19 (17.3)	7 (6.4)^a	2 (1.8)^b
3 score	4 (3.6)	2 (1.8)	0
Myoclonus				0.671
0 grade	108 (98.2)	105 (95.5)	104 (94.5)
1 grade	2 (1.8)	4 (3.6)	5 (4.5)
2 grade	0	1 (0.9)	1 (0.9)
3 grade	0	0	0
Nausea	18 (16.3)	19 (17.3)	13 (11.8)	0.725
Vomiting	6 (5.5)	8 (7.3)	7 (6.3)	0.581

^aP < 0.05, P group vs 0.1EP group.

^bP < 0.05, P group vs 0.15EP group.

^cP < 0.05, 0.1EP group vs 0.15EP group.

Citation: Luo HR, Chen AD, Lin JF, Ye P, Chen YJ, Lin MX, Chen PZ, Chen XH, Zheng XC. Effect of etomidate added to propofol target-controlled infusion in bidirectional endoscopy: A randomized clinical trial. World J Gastrointest Endosc 2025; 17(2): 100722
URL: https://www.wjgnet.com/1948-5190/full/v17/i2/100722.htm
DOI: https://dx.doi.org/10.4253/wjge.v17.i2.100722