Effect of vinegar supplementation on patients with esophageal lesions lightly stained with Lugol’s iodine solution: Prospective single-centre trial

doi:10.4253/wjge.v16.i5.259

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May 16, 2024 (publication date) through Jun 21, 2024

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Prospective Study

World J Gastrointest Endosc. May 16, 2024; 16(5): 259-272
Published online May 16, 2024. doi: 10.4253/wjge.v16.i5.259

Table 4 Hazard ratio and 95%CI of clinical therapeutic outcomes (per-protocol population)

Therapeutic effect	HR (95%CI)	Multivariable adjusted HR (95%CI)¹
Endoscopic characteristics improved
Conventional group	1.00	1.00
Experimental group	2.307 (1.202, 4.426)^a	2.545 (1.282, 5.052)^b
Endoscopic characteristics deteriorate
Conventional group	1.00	1.00
Experimental group	0.793 (0.306, 2.055)	0.979 (0.923, 1.037)
Biopsy pathology improved
Conventional group	1.00	1.00
Experimental group	3.320 (1.295, 8.507)^a	3.186 (1.179, 8.605)^a
Biopsy pathology deteriorate
Conventional group	1.00	1.00
Experimental group	0.795 (0.259, 2.440)	0.969 (0.896, 1.048)
HGIN or early cancer
Conventional group	1.00	1.00
Experimental group	0.382 (0.079, 1.846)	0.750 (0.140, 4.015)

^aP 0.05.

^bP 0.01.

¹adjusted by age, sex, lesion size, lesion location and biopsy characteristics.

HR: Hazard ratio; HGIN: High-grade intraepithelial neoplasia.

Citation: Gao Y, Ye LS, Li X, Yu B, Liao K, Xie J, Du J, Zhang QY, Hu B. Effect of vinegar supplementation on patients with esophageal lesions lightly stained with Lugol’s iodine solution: Prospective single-centre trial. World J Gastrointest Endosc 2024; 16(5): 259-272
URL: https://www.wjgnet.com/1948-5190/full/v16/i5/259.htm
DOI: https://dx.doi.org/10.4253/wjge.v16.i5.259