Prospective Study
Copyright ©The Author(s) 2024.
World J Gastrointest Endosc. May 16, 2024; 16(5): 259-272
Published online May 16, 2024. doi: 10.4253/wjge.v16.i5.259
Table 2 Characteristics of patients and lesions (per-protocol population), n (%)
Characteristics
Experimental group
Conventional group
P value
No. of participants8076
Age, mean ± SD, yr59.69 ± 8.4759.32 ± 9.220.7931
BMI, mean ± SD, kg/m223.93 ± 3.4323.49 ± 2.280.0701
Sex0.5352
        Male49 (61.25)47 (61.84)
        Female31 (38.75)29 (38.16)
Basic diseases
        Diabetes9 (11.25)8 (10.53)0.5452
        Hypertension13 (16.25)6 (7.89)0.1432
        Coronary heart disease3 (3.75)4 (5.26)0.9492
Family history of esophageal cancer or stomach cancer0.9842
        No62 (77.50)59 (77.63)
        Yes18 (22.50)17 (22.37)
Smoking0.8632
        No-smoker41 (51.25)40 (52.63)
        Smoker39 (48.75)36 (47.37)
Smoking index0.6872
        ≤ 20014 (17.50)10 (13.16)
        200-40014 (17.50)13 (17.11)
        ≥ 40011 (13.75)13 (17.11)
Alcohol drinking0.8362
        No-drinker35 (45.75)32 (42.11)
        Drinker45 (56.25)44 (57.89)
Alcohol ingestion, g/d0.9362
        ≤ 20 21 (26.25)19 (25.00)
        20-6013 (16.25)13 (17.11)
        ≥ 6011 (13.75)12 (15.79)
Prefer hot dishes/hot tea0.2872
        No46 (57.50)50 (65.79)
        Yes34 (42.50)26 (34.21)
Prefer spicy food0.2102
        No70 (8.75)71 (93.42)
        Yes10 (12.50)5 (6.58)
Prefer pickled dishes0.0872
        No71 (88.75)73 (96.05)
        Yes9 (11.25)3 (3.95)
Multiple Lugol’s voiding lesions0.30182
        No54 (67.50)57 (75.00)
        Yes26 (32.50)19 (25.00)
Lesion location0.1942
        Upper thoracic esophagus12 (15.00)8 (10.53)
        Middle thoracic esophagus39 (48.75)48 (63.16)
        Lower thoracic esophagus29 (36.25)20 (26.32)
Maximum diameter0.3792
        Lesion size ≤ 0.5 cm60 (75.00)52 (68.42)
        Lesion size > 0.5 cm20 (25.00)24 (31.58)
Morphology0.5182
        Quasi circular29 (36.25)28 (36.84)
        Bar-type3 (3.75)6 (7.89)
        Irregular shape48 (60.00)42 (55.26)
Biopsy pathology0.4772
        Squamous epithelial hyperplasia71 (88.75)70 (92.11)
        Low grade intraepithelial neoplasia9 (11.25)6 (7.89)
Follow-up time29.53 ± 5.7331.00 ± 5.520.5141