Safety and efficacy of peroral endoscopic myotomy for treating achalasia in pediatric and geriatric patients: A meta-analysis

Table 2 Clinical outcomes of the studies on peroral endoscopic myotomy for achalasia in pediatric patients, n (%)

Ref.	Technical success	Clinical success	GERD	Adverse events
Li et al[19], 2015	9/9 (100)	9/9 (100)	1/9 (11.1)	2/9 (11.1)
Chen et al[20], 2015	26/27 (96.3)	26/26 (100)	5/26 (19.2)	9/26 (34.6) (Cumulative adverse events on CT scan: 53)
Caldaro et al[21], 2015	9/9 (100)	9/9 (100)	1/9 (11.1)	1/9 (11.1)
Tang et al[22], 2015	5/5 (100)	4/4 (100)	0 (0)	0 (0)
Tan et al[23], 2016	12/12 (100)	12/12 (100)	2/12 (16.7)	3/12 (8.3)
Stavropoulos et al[24], 2017	10/10 (100)	10/10 (100)	2/5 (40)	4/10 (40)
Zangen et al[25], 2017	5/5 (100)	5/5 (100)	0 (0)	0 (0)
Kethman et al[26], 2018	10/10 (100)	8/10 (80)	0 (0)	3/10 (30)
Miao et al[27], 2018	21/21 (100)	21/21 (100)	6/21 (28.6)	12/21 (57.1)
Korrapati et al[28], 2018	15/15 (100)	15/15 (100)	0 (0)	2/15 (13.3)
Nishimoto et al[29], 2018	13/13 (100)	12/13 (92.3)	-	2/13 (15.4)
Mangiola et al[30], 2018	25/26 (96.2)	26/26 (100)	4/17 (23.5)	6/26 (23.1)
Yamashita et al[31], 2018	7/7 (100)	7/7 (100)	-	0 (0)
Choné et al[32], 2019	116/117 (99.1)	106/117 (90.6)	17/117 (21.4)	7/117 (8.5)
Nabi et al[33], 2019	43/44 (97.7)	40/44 (90.9)	11/20 (55)	11/43 (25.6)
Liu et al[34], 2019	129/130 (99.2)	108/113 (95.6)	30/111 (27.0)	5/130 (3.8)
Saez et al[35], 2020	5/5 (100)	5/5 (100)	2/5 (40)	0 (0)
Wood et al[36], 2020	21/21 (100)	21/21 (100)	-	6/21 (28.6)
Peng et al[37], 2022	24/24 (100)	23/24 (95.8)	5/21 (23.8)	0 (0)
Petrosyan et al[38], 2022	37/37 (100)	37/37 (100)	3/37 (8.1)	9/37 (24.3)

GERD: Gastroesophageal reflux disease; CT: Computed tomography.