Multicenter evaluation of recurrence in endoscopic submucosal dissection and endoscopic mucosal resection in the colon: A Western perspective

Table 2 Characteristics of polyp with follow-up, by intervention, n (%)

N = 287	ESD (n = 77)	Knife-assisted endoscopic resection (n = 32)	EMR (n = 178)	P value
Size of polyp, mm (mean ± SD)	37.2 (19.7)	32.7 (8.7)	31.4 (11.5)	0.010
En bloc	69 (89.7)	8 (25.0)	27 (15.2)	< 0.001
Location of polyp				< 0.001
Cecum	10 (13.0)	7 (21.9)	47 (26.4)
Ascending	13 (16.9)	12 (37.5)	63 (35.4)
Transverse	8 (10.4)	6 (18.8)	45 (25.3)
Descending	2 (2.6)	4 (12.5)	12 (6.7)
Sigmoid	10 (13.0)	1 (3.1)	5 (2.8)
Rectum	34 (44.2)	2 (6.3)	6 (3.4)
Paris classification				< 0.001
Is	57 (74.0)	18 (56.3)	64 (36.0)
IIa	16 (20.8)	9 (28.1)	102 (57.3)
IIb	0 (0.0)	1 (3.1)	2 (1.1)
IIa+c	2 (2.6)	1 (3.1)	2 (1.1)
IIc	0 (0.0)	1 (3.1)	0 (0.0)
Isp	2 (2.6)	2 (6.3)	8 (4.5)
Pathology				< 0.001
Non-neoplastic	0 (0.0)	1 (3.1)	10 (5.6)
Neoplastic, no high-grade dysplasia	50 (64.9)	25 (78.1)	152 (85.4)
High-grade dysplasia	17 (22.1)	6 (18.8)	12 (6.7)
Cancer	10 (13.0)	0 (0.0)	4 (2.2)
First follow-up, days (mean ± SD)	456.8 (326.1)	365.0 (230.2)	516.2 (377.7)	0.061
Recurrence	1 (1.3)	0 (0.0)	23 (12.9)	0.0017
Complete resection				< 0.001
R0	57 (74.0)	6 (18.8)	8 (4.5)
R1	18 (23.4)	26 (81.3)	156 (87.6)
Rx	2 (2.6)	0 (0.0)	14 (7.9)

EMR: Endoscopic mucosal resection; ESD: Endoscopic submucosal dissection.