Endoscopic biliary treatment of unresectable cholangiocarcinoma: A meta-analysis of survival outcomes and systematic review

Table 2 Procedural and survival outcomes of individual studies

Ref.	Total patients		Technical success		Major adverse events		Mean survival (mean ± SD)		P valuea
	Stent only	RFA-stent	Stent only	RFA-stent	Stent only	RFA-stent	Stent only	RFA-stent
Endoscopic
Sampath et al[23], 2016	15	10	-	100	8	9	4.7 ± 5.5	12 ± 5.9	0.001
Hu et al[21], 2016	31	32	-	-	22	26	5.7 ± 0.5	10.4 ± 1.2	0.001
Yang et al[22], 2018	33	32	100	100	3	2	8.3 ± 0.5	13.2 ± 0.6	< 0.001
Bokemeyer et al[24], 2019	22	20	100	100	10	4	7.4 ± 0.9	11.4 ± 1.9	0.046
Percutaneous
Wu et al[26], 2017	36	35	-	100	5	0	6.5 ± 2.6	8.4 ± 2.3	0.80
Cui et al[25], 2017	14	25	-	-	-	-	4.5 ± 2.1	6.7 ± 5.3	0.30

^aP value as it relates to mean survival in each respective study. SD: Standard deviation; RFA: Radiofrequency ablation.