Thoracoscopic esophagectomy is related to better outcomes in early adenocarcinoma of esophagogastric junction tumors

Table 4 Univariate and multivariate analysis for disease-free survival and overall survival

Disease-free survival	Univariate analysis			Multivariate analysis
Variables	HR	95%CI	P value	HR	95%CI	P value
Male (vs female)	0.99	0.47–2.08	0.975
Age (< 62 yr vs > 62 yr)	0.87	0.56–3.14	0.873
Siewert 1 vs 2	1.11	0.14–8.89	0.921
TH vs TT (1, 2A)	1.71	1.01–2.90	0.046	1.73	1.00–2.99	0.049
Post-operative complications	1.22	0.56-2.06	0.961
G3 (vs G1/G2)	1.14	0.61–2.13	0.690
LN+/LN-	2.61	1.71-3.56	0.001	1.77	0.99-3.24	0.101
pT3/pT4 status (vs pT0/T1/pT2)	2.21	1.86–7.31	0.003	1.56	0.97-3.89	0.102
pN+ (vs pN0)	2.54	1.57-5.78	0.05	1.43	0.88-3.32	0.103
Pathological exam
Lymphatic	0.78	0.39-1.29	0.783
Venous	1.67	0.35-2.72	0.246
Neural	0.78	0.67-1.89	0.183
Overall survival	Univariate analysis		Multivariate analysis
Variables	HR	95%CI	P value	HR	95%CI	P value
Age (< 62 yr vs > 62 yr)	0.98	0.89-5.13	0.821
Siewert 1 vs 2	1.31	0.16-10.68	0.799
TH vs TT (1, 2A)	2.01	1.19-3.39	0.009	1.79	1.03-3.09	0.038
Post-operative complications	1.03	0.60-1.74	0.927
G3 (vs G1/G2)	2.37	1.36-4.16	0.003	2.54	1.33-4.82	0.005
LN+/LN-	1.72	1.00-3.48	0.050	1.21	0.87-3.46	0.732
pT3/pT4 status (vs pT0/T1/pT2)	5.95	1.81-19.61	0.003	9.96	2.43-40.74	0.001
pN+ (vs pN0)	1.68	1.38-3.90	0.002	1.18	0.86-4.99	0.735
Pathological exam
Lymphatic	0.47	0.23-1.78	0.109
Venous	0.49	0.20-1.06	0.076
Neural	1.80	0.96-3.35	0.065