Meta-analysis and trial sequential analysis of randomized evidence comparing general anesthesia vs regional anesthesia for laparoscopic cholecystectomy

Table 1 Summary characteristics of included studies

Ref.	Year	Country	Journal	Design	Total number of patients	GA	RA
Majedi et al[15]	2019	Iran	Advanced Biomedical Research	RCT	80	40	40
Sharaf et al[19]	2018	Pakistan	Anaesthesia, Pain and Intensive Care	RCT	120	60	60
Donmez et al[11]	2017	Turkey	Annals of Surgical Treatment and Research	RCT	49	25	24
Kalaivani et al[14]	2014	India	Journal of Clinical and Diagnostic Research	RCT	50	25	25
Prasad et al[17]	2014	India	Journal of Evolution of Medical and Dental Sciences	RCT	60	30	30
Ellakany et al[12]	2013	Egypt	Egyptian Journal of Anaesthesia	RCT	40	20	20
Tiwari et al[20]	2013	India	Journal of Minimal Access Surgery	RCT	235	114	110
Bessa et al[5]	2012	Egypt	Journal of Laparoendoscopic and Advanced Surgical Techniques	RCT	180	90	90
Ross et al[18]	2012	United States	Surgical Endoscopy	RCT	20	10	10
Mehta et al[16]	2010	India	Anesthesia, Essays and Researches	RCT	60	30	30
Imbelloni et al[13]	2010	Brazil	Revista Brasileira de Anestesiologia	RCT	68	33	35
Bessa et al[21]	2010	Egypt	Journal of Laparoendoscopic and Advanced Surgical Techniques	RCT	60	30	30
Tzovaras et al[4]	2008	Greece	Archives of Surgery	RCT	100	50	50

RCT: Randomized controlled trial; GA: General anesthesia; RA: Regional anesthesia.