Molecular analysis of pancreatic cystic neoplasm in routine clinical practice

doi:10.4253/wjge.v13.i2.56

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World Journal of Gastrointestinal Endoscopy

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World J Gastrointest Endosc. Feb 16, 2021; 13(2): 56-71
Published online Feb 16, 2021. doi: 10.4253/wjge.v13.i2.56

Table 4 Molecular analysis

	Non-mucinous					Mucinous
	PCN5	PCN15	PCN18	PCN20	PCN33	PCN0	PCN1	PCN2	PCN3	PCN4	PCN7	PCN11	PCN13	PCN14	PCN16	PCN17	PCN19	PCN21	PCN24	PCN25	PCN29	PCN30	PCN34
KRAS	M	M	N	N	M	M	N	N	N	N	M	N	N	N	N	M	N	N	N	M	M	N	N
GNAS	M	M	N	N	M	N	N	N	N	N	N	N	M	N	N	M	M	N	M	M	M	M	M
VHL	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
P53	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
PIK3R1	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	N	M	M	M
EGFR	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
ALK	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
NOTCH1	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
GNA11	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
CDKN2A	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
APC	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
FGFR2	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
IDH1	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	N	M	M	M	M	M	M
PIK3CA	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
KIT	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
MET	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
FGFR1	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
ROS1	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
GNAQ	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
PDGFRA	M	M	M	M	M	M	M	M	N	M	M	M	M	M	M	M	M	M	M	M	N	M	N
FGFR3	N	M	M	M	M	M	M	M	M	M	M	M	M	N	M	M	M	M	M	M	M	M	M
RNF43	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
RET	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	N
ERBB2	M	M	M	M	M	M	M	M	N	M	M	M	M	M	M	M	M	M	M	M	M	M	M
DDR2	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
BRAF	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	N	M
ESR1	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
FGFBR2	M	M	M	M	M	M	N	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
FBXW7	M	M	N	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
FOXL2	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
MAP2K1	M	M	M	M	M	M	M	N	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
AKT1	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
CTNNB1	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
SMAD4	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
PTEN	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
NRAS	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
IDH2	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
HRAS	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M
CDH1	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M	M

PCN: Pancreatic cystic neoplasm. M: Mutated; N: Not-mutated.

Citation: Herranz Pérez R, de la Morena López F, Majano Rodríguez PL, Molina Jiménez F, Vega Piris L, Santander Vaquero C. Molecular analysis of pancreatic cystic neoplasm in routine clinical practice. World J Gastrointest Endosc 2021; 13(2): 56-71
URL: https://www.wjgnet.com/1948-5190/full/v13/i2/56.htm
DOI: https://dx.doi.org/10.4253/wjge.v13.i2.56