Efficacy and tolerability of high and low-volume bowel preparation compared: A real-life single-blinded large-population study

doi:10.4253/wjge.v13.i12.659

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Endosc. Dec 16, 2021; 13(12): 659-672
Published online Dec 16, 2021. doi: 10.4253/wjge.v13.i12.659

Table 8 Tolerability of high and low-volume preparations according to different schedules, n (%)

	High volume one-day (n = 482)	High volume split dose (n = 389)	P value¹	Low volume one-day (n = 583)	Low volume split dose (n = 361)	P value¹
Global tolerance, VAS score², median (interquartile range)	7 (5-8)	7 (5-9)	0.006³	7 (5-9)	7 (5-9)	0.033
Incomplete preparation	37 (7.9)	30 (7.9)	0.994	31 (5.5)	18 (5.2)	0.840
Any symptom during preparation	211 (43.8)	158 (40.6)	0.384	324 (55.6)	167 (46.3)	0.005³
Bloating	103 (21.4)	80 (20.6)	0.772	126 (21.6)	54 (14.9)	0.011³
Nausea	112 (23.2)	75 (19.3)	0.158	196 (33.6)	97 (26.9)	0.029³
Vomiting	33 (6.9)	22 (5.7)	0.473	73 (12.5)	46 (12.7)	0.921
Abdominal pain	54 (11.2)	50 (12.9)	0.455	105 (18.0)	72 (19.9)	0.459

¹P value degrees of freedom = 1.

²Visual Analogue Scale: 0 absolutely non-tolerated, 10 perfectly tolerated. Data available for 1772 patients.

³Significant different.

VAS: Visual analogue scale.

Citation: Occhipinti V, Soriani P, Bagolini F, Milani V, Rondonotti E, Annunziata ML, Cavallaro F, Vavassori S, Vecchi M, Pastorelli L, Tontini GE. Efficacy and tolerability of high and low-volume bowel preparation compared: A real-life single-blinded large-population study. World J Gastrointest Endosc 2021; 13(12): 659-672
URL: https://www.wjgnet.com/1948-5190/full/v13/i12/659.htm
DOI: https://dx.doi.org/10.4253/wjge.v13.i12.659