Kyoto classification in patients who developed multiple gastric carcinomas after Helicobacter pylori eradication

Table 2 Characteristics of the 45 gastric cancer after Helicobacter pylori eradication

Characteristics	Total (n = 45)	Single (n = 38)	Multiple (n = 7)	P value
Mean age (range), yr	67.0 (43-86)	65.6 (43-86)	74.7 (63-84)	0.039a
Sex, n (%)				0.61
Female	17 (37.7)	15 (39.4)	2 (28.5)
Male	28 (62.2)	23 (60.5)	5 (71.4)
Kyoto score, average	4.02	3.81	5.14	0.016a
Atrophic gastritis, score, n (%)	1.71	1.65	2.00	0.77
None, 0	1 (2.22)	1 (2.63)	0
C-1, 0	0	0	0
C-2, 1	7 (15.5)	7 (18.4)	0
C-3, 1	4 (8.88)	4 (10.5)	0
O-1, 2	7 (15.5)	6 (15.7)	1 (14.2)
O-2, 2	7 (15.5)	6 (15.7)	1 (14.)
O-3, 2	19 (42.2)	14 (36.8)	5 (71.4)
Intestinal metaplasia, score, n (%)	1.28	1.15	2.00	0.048a
None, 0	12 (26.6)	12 (31.5)	0
Antrum, 1	8 (17.7)	8 (21.0)	0
Corpus, 2	25 (55.5)	18 (47.3)	7 (100)
Enlarged folds, score, n (%)	0.06	0.07	0	0.44
None, 0	42 (93.3)	35 (92.1)	7 (100)
Present, 1	3 (6.66)	3 (7.89)	0
Nodularity, score, n (%)	0	0	0	1.00
None, 0	45 (100)	38 (100)	7 (100)
Present, 1	0	0	0
Diffuse redness, score, n (%)	0.95	0.92	1.14	0.65
None, 0	3 (6.66)	3 (7.89)	0
With RAC, 1	41 (91.1)	35 (92.1)	6 (85.7)
Without RAC, 2	1 (2.22)	0	1 (14.2)
Map like redness, yes	27 (58.6)	22 (56.4)	5 (71.4)	0.68
Mean size (range), mm	14.8 (1.0-120)	15.5 (1-120)	11.1 (1.0-35)	0.46
Pathology, n (%)
Intestinal type	42 (93.3)	35 (92.1)	7 (100)	0.44
Diffuse type	3 (6.66)	3 (7.89)	0
Stage, n (%)				0.98
I	43 (95.5)	36 (94.7)	7 (100)
II	1 (2.22)	1 (2.63)	0
III	1 (2.22)	1 (2.63)	0
IV	0	0	0
Treatment for gastric cancer, n (%)
Endoscopy	43 (95.5)	36 (94.7)	7 (100)	0.54
Surgery	2 (4.44)	2 (5.26)	0
Chemotherapy	0	0	0
Best supportive care	0	0	0

^aStatistically significant. RAC: Regular arrangement of collecting venule.