Colon mucosal neoplasia referred for endoscopic mucosal resection: Recurrence of adenomas and prediction of submucosal invasion

Table 2 Factors associated with submucosal invasion

Factors	No SMI (%)	SMI (%)	P value
	n = 477	n = 23
Size (mm)	30 (12.38)	40 (18.14)	aP < 0.05
Age (yr)	68 (9.7)	69 (10.6)	0.5288
Height (cm)	170 (10.38)	170 (11.04)	0.9185
Weight (kg)	80 (22.32)	87 (30.74)	0.518
BMI	28 (6.77)	30 (8.3)	0.31
Colonoscopy duration (min)	43 (25.03)	56 (21.49)	0.063
Gender			0.6816
Male	249 (52.2)	11 (47.83)
Female	228 (47.8)	12 (52.17)
ASA			0.6912
1	14 (2.94)	0 (0)
2	333 (69.81)	17 (73.91)
3	130 (27.25)	6 (26.09)
Size group			0.1663
20 mm	86 (18.03)	3 (13.04)
21-30 mm	192 (40.25)	6 (26.09)
31-40 mm	102 (21.38)	5 (21.74)
> 40 mm	97 (20.34)	9 (39.13)
Paris classification			bP < 0.01
Ip (pedunculated)	32 (6.7)	2 (8.7)
0-IIa (flat elevation of mucosa)	308 (64.57)	8 (26.09)
0-IIb (flat mucosal change)	68 (14.25)	0 (0)
0-IIc (flat mucosal depression)	1 (0.21)	2 (0)
0-IIa + c (flat elevation with central depression)	22 (4.61)	4 (17.39)
0-IIa + Is (flat elevation with raised broad based nodule)	46 (9.64)	7 (30.43)
Kudo Pit Pattern			cP < 0.01
I	3 (0.63)	0 (0)
II	10 (2.1)	0 (0)
IIIs	190 (39.83)	2(8.7)
IIIL	164 (34.38)	8 (34.78)
IV	58 (12.16)	4 (17.39)
V	15 (3.14)	4 (17.39)
IIIs + IIIL	18 (3.77)	2 (8.7)
IIIs + IV	4 (0.84)	0 (0)
IIIL + IV, Vn	15 (3.14)	3 (13.04)
Morphology			0.3404
Granular	247 (51.78)	13 (56.52)
Non granular	199 (41.72)	7 (30.43)
Mixed	31 (6.5)	3 (13.04)
Location			0.6017
Rectum (< 5 cm from anus)	4 (0.84)	0 (0)
Rectum (> 5 cm from anus)	27 (5.66)	4 (17.39)
Sigmoid	41 (8.6)	4 (17.39)
Descending colon	24 (5.03)	1 (4.35)
Splenic flexure	6 (1.26)	0 (0)
Transverse	62 (13)	3 (13.04)
Hepatic flexure	38 (7.97)	1 (4.35)
Ascending colon	155 (32.49)	6 (26.09)
Cecum	98 (20.55)	4 (17.39)
Ileocecal valve involved	18 (3.77)	0 (0)
Appendiceal orifice involved	4 (0.84)	0 (0)

Categorical variables were presented as frequency (%). SMI: Submucosal invasion; ICV: Ileocecal valve.