Nonsteroidal anti-inflammatory drug effectivity in preventing post-endoscopic retrograde cholangiopancreatography pancreatitis: A systematic review and meta-analysis

Table 2 Characteristics of 26 randomized controlled trials, including comparison group (number), administration time (before, during, after, and before/after endoscopic retrograde cholangiopancreatography)

Ref.	Comparison (n)	Administration time (after, before, and during)	n	Intervention
Andrade et al[24], 2015	Glycerin (84)	Before ERCP	166	82
Bhatia et al[6], 2011	Glyceryl trinitrate (127)	Before ERCP	254	127
Cheon et al[10], 2007	Placebo SN (102)	Before and after ERCP	207	105
Döbrönte et al[7], 2014	Placebo SN (318)	After ERCP	665	347
Elmunzer et al[25], 2012	Placebo SN (307)	After ERCP	602	295
Hauser et al[11], 2016	Ceftazidime (143)	Before ERCP	272	129
Ishiwatari et al[12]., 2016	Placebo SN (214)	Before and after ERCP	430	216
Kato et al[31], 2017	Saline solution (85)	Before ERCP	170	85
Kato et al[13]., 2019	None (152)	Before ERCP	303	151
Khoshbaten et al[14], 2008	Placebo SN (50)	Before ERCP	100	50
Leerhøy et al[15], 2016	None (394)	After ERCP	772	378
Levenick et al[26], 2016	Placebo SN (226)	During ERCP	449	223
Li et al[27], 2019	Glycerin (50)	Before ERCP	100	50
Lua et al[16], 2015	None (75)	After ERCP	144	69
Mansour et al[32], 2016	Placebo SN (162)	Before ERCP	324	162
Masjedizadeh et al[26], 2017	Placebo lactated Ringer’s solution (124)	Before ERCP	186	62
Montaño et al[23], 2007	Glycerin (75)	Before ERCP	150	75
Hosseini et al[28], 2016	Saline solution (205)	Before ERCP	406	201
Murray et al[17], 2003	Placebo SN (110)	After ERCP	220	110
Otsuka et al[18], 2012	Saline solution (53)	Before ERCP	104	51
Park et al[21], 2014	Saline solution (170)	After ERCP	343	173
Patai et al[29], 2015	Placebo SN (269)	Before ERCP	539	270
Quadros et al[33], 2016	Saline solution (253)	After ERCP	477	224
Senol et al[19], 2009	Placebo SN (40)	After ERCP	80	40
Sotoudehmanesh et al[30], 2007	Placebo SN (245)	After ERCP	490	245
Uçar et al[20], 2016	None (50)	Before ERCP	150	100
Total	-	-	8103	4020

n = total number of patients, and number of patient intervention. ERCP: Endoscopic retrograde cholangiopancreatography.