Anticoagulation and antiplatelet management in gastrointestinal endoscopy: A review of current evidence

Table 38 Endoscopic submucosal dissection

Ref.	Year	Country	Study design	n	Procedure	Medication	Relative risk
Sato et al[57]	2017	Japan	Retrospective	75 (2378)	ESD	DAPT (ceased thienopyridine before and bridged with aspirin monotherapy)	Incidence of PPB 30.7%
Kono et al[58]	2018	Japan	Retrospective	6 (872)	ESD	DAPT (ceased thienopyridine 7 d before and bridged with aspirin monotherapy)	Incidence of PPB 67.7%
Oh et al[116]	2018	South Korea	Retrospective	51 (215)	ESD	DAPT either: (1) Ceased 5-7 d before (discontinuation group); (2) Ceased 0-4 d before (continuation group)	Incidence of delayed PPB 27.5% (14/51)
Harada et al[117]	2019	Japan	Retrospective	59 (597)	ESD	DAPT either: (1) Ceased thienopyridine 5 d before and bridged with aspirin monotherapy (high-risk conditions); (2) DAPT ceased > 5 d before (low-risk conditions)	Incidence of PPB 23.1% (aspirin monotherapy bridging). Incidence of PPB 5.0% (DAPT ceased)

ESD: Endoscopic submucosal dissection; DAPT: Dual antiplatelet therapy; PPB: Post-procedural bleeding.