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©The Author(s) 2020.
World J Gastrointest Endosc. Oct 16, 2020; 12(10): 365-377
Published online Oct 16, 2020. doi: 10.4253/wjge.v12.i10.365
Published online Oct 16, 2020. doi: 10.4253/wjge.v12.i10.365
Table 5 Updated summary of published randomized controlled trials of endoscopic variceal ligation vs injection sclerotherapy
Ref. | Year | Number of patients | Number in each group | Control of bleeding | Varices eradicated | Eradication sessions | Rebleeding | Major complications | Variceal recurrence | Survival | ||||||||
EVL | IST | EVL | IST | EVL | IST | EVL | IST | EVL | IST | EVL | IST | EVL | IST | EVL | IST | |||
Stiegmann et al[21] | 1992 | 129 | 64 | 65 | 86% | 77% | 55% | 56% | 4 | 5 | 36% | 48% | 2% | 22% | 33% | 50% | 72% | 55% |
Laine et al[22] | 1993 | 77 | 38 | 39 | 89% | 89% | 59% | 69% | 4.1 | 6.2 | 24% | 31% | 24% | 56% | - | - | 89% | 85% |
Gimson et al[23] | 1993 | 103 | 54 | 49 | 91% | 92% | 82% | 71% | 3.4 | 4.9 | 30% | 53% | 69% | 65% | - | - | 52% | 18% |
Lo et al[24] | 1995 | 120 | 61 | 59 | 94% | 80% | 74% | 63% | 3.8 | 6.5 | 11% | 36% | 3.3% | 19% | - | - | 84% | 68% |
Hou et al[25] | 1995 | 134 | 67 | 67 | 100% | 88% | 87% | 79% | 3.5 | 4.6 | 18% | 33% | 4% | 22% | 48% | 30% | 79% | 84% |
Sarin et al[26] | 1997 | 95 | 47 | 48 | 86% | 80% | 94% | 94% | 4.1 | 5.2 | 6.4% | 20.8% | 45% | 50% | 28.7% | 7.5% | 93% | 89% |
Baroncini et al[27] | 1997 | 111 | 57 | 54 | - | - | 93% | 93% | 3.5 | 4.0 | 16% | 19% | 11% | 31% | 30% | 13% | 79% | 78% |
Avgerinos et al[28] | 1997 | 77 | 37 | 40 | - | - | 95% | 98% | 3.7 | 5.8 | 27% | 48% | 35% | 60% | 31% | 44% | 80% | 79% |
Lo et al[19] | 1997 | 71 | 37 | 34 | 97% | 76% | - | - | - | - | 17% | 33% | 5% | 29% | - | - | 81% | 65% |
Siqueira et al[29] | 1998 | 40 | 20 | 20 | - | - | 90% | 100% | 3.1 | 3.7 | 0% | 5% | - | - | 0% | 0% | 100% | 95% |
De la Pena et al[30] | 1999 | 88 | 42 | 46 | - | - | 79% | 71% | 5.3 | 6.6 | 31% | 50% | 14% | 41% | 47% | 23% | 81% | 78% |
Masci et al[31] | 1999 | 100 | 50 | 50 | - | - | 88% | 82% | 3.4 | 5.3 | 12% | 42% | 18% | 38% | 32% | 27% | 80% | 78% |
Fakhry et al[32] | 2000 | 84 | 43 | 41 | 94% | 94% | - | - | 2.8 | 4.8 | 16% | 15% | 2% | 65% | 21% | 20% | 93% | 93% |
Zargar et al[33] | 2005 | 73 | 37 | 36 | 100% | 83% | 95% | 92% | 3.7 | 7.7 | 3% | 19% | 3% | 22% | 11% | 9% | - | - |
Villanueva et al[20] | 2006 | 179 | 90 | 89 | 96% | 85% | - | - | - | - | 7% | 12% | 4% | 13% | - | - | 87% | 79% |
Luz et al[34] | 2011 | 100 | 50 | 50 | 92% | 96% | - | - | - | - | 22% | 14% | - | - | - | - | 77% | 80% |
Ali et al[35] | 2017 | 124 | 60 | 64 | 100% | 100% | 87% | 80% | - | - | 23% | 28% | 10% | 27% | - | - | 78% | 72% |
- Citation: Krige J, Jonas E, Kotze U, Kloppers C, Gandhi K, Allam H, Bernon M, Burmeister S, Setshedi M. Defining the advantages and exposing the limitations of endoscopic variceal ligation in controlling acute bleeding and achieving complete variceal eradication. World J Gastrointest Endosc 2020; 12(10): 365-377
- URL: https://www.wjgnet.com/1948-5190/full/v12/i10/365.htm
- DOI: https://dx.doi.org/10.4253/wjge.v12.i10.365