Clinical outcomes of endoscopic management of pancreatic fluid collections in cirrhotics vs non-cirrhotics: A comparative study

doi:10.4253/wjge.v11.i6.403

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World Journal of Gastrointestinal Endoscopy

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Retrospective Study

World J Gastrointest Endosc. Jun 16, 2019; 11(6): 403-412
Published online Jun 16, 2019. doi: 10.4253/wjge.v11.i6.403

Table 1 Demographic and clinical data

Factor	Non-cirrhotic (n = 25)	Cirrhotic (n = 5)	Difference (95%CI)	P value
Age	48.8 ± 15.8	57.8 ± 13.7	9.0 (-6.6, 24.6)	0.25^a
Gender				0.62^d
Male	14 (56.0)	4 (80.0)	24.0 (-26.1, 71.6)
Female	11 (44.0)	1 (20.0)
Anti-platelets	4 (16.0)	3 (60.0)	44.0 (-6.3, 85.3)	0.068^d
Charlson co-morbidity index	80.4 ± 29.4	50.4 ± 37.2	-30.0 (-60.8, 0.73)	0.055^a
Type of PFC				0.99^d
WON	10 (40.0)	2 (40.0)	0.00 (-52.2, 52.2)
Pseudocyst	15 (60.0)	3 (60.0)
Location of PFC				0.62^d
Head	9 (36.0)	1 (20.0)	-16.0 (-64.4, 33.8)
Body	14 (56.0)	3 (60.0)	4.0 (-45.0, 52.4)
Tail	2 (8.0)	1 (20.0)	12.0 (-37.5, 60.1)
Size of PFC (mm)	122.9 ± 61.2	125.2 ± 68.4	2.3 (-60.2, 64.8)	0.94^a
Extension of fluid collection to paracolic gutter	6 (24.0)	1 (20.0)	-4.0 (-52.4, 45.0)	0.99^d
Pancreatic Duct on imaging				0.99^d
No leak	18 (72.0)	4 (80.0)	8.0 (-41.3, 56.2)
Leak	3 (12.0)	0 (0.0)	-12.0 (-60.1, 37.5)
Complete disruption	4 (16.0)	1 (20.0)	4.0 (-45.0, 52.4)
Indication of collection drainage				0.17^d
Gastric outlet obstruction	7 (28.0)	2 (40.0)	12.0 (-37.5, 60.1)
Abdominal pain	12 (48.0)	1 (20.0)	-28.0 (-71.6, 22.2)
Early satiety	4 (16.0)	0 (0.0)	-16.0 (-64.4, 33.8)
Rapid increase in size	2 (8.0)	1 (20.0)	12.0 (-37.5, 60.1)
Jaundice	0 (0.0)	1 (20.0)	20.0 (-29.9, 71.6)
Etiology of pancreatitis				0.24^d
Gallstones	10 (40.0)	1 (20.0)	-20.0 (-71.6, 29.9)
Alcohol	8 (32.0)	4 (80.0)	48.0 (-2.2, 85.3)
Other	7 (28.0)	0 (0.0)	-28.0 (-71.6, 22.2)
Platelets	248.7 ± 101.3	132.6 ± 57.5	-116.1 (-214.5, -17.7)	0.023^a
Alkaline Phosphatase	103.3 ± 57.3	790.8 ± 1461.4	687.5 (54.8, 1320.2)	0.034^a
ALT	31.2 ± 36.4	100.6 ± 169.0	69.4 (-11.1, 149.9)	0.088^a
AST	36.5 ± 50.9	173.6 ± 272.9	137.1 (10.0, 264.2)	0.036^a
Bilirubin	0.61 ± 0.48	3.3 ± 3.1	2.7 (1.2, 4.1)	< 0.001^a
INR	1.1 ± 0.12	1.3 ± 0.30	0.24 (0.06, 0.42)	0.012^a

Statistics presented as mean ± SD, or n (%). P values:

^aANOVA; ^bFisher’s exact test. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; PFC: Pancreatic fluid collection; INR: International normalized ratio; WON: Walled off necrosis.

Citation: Laique S, Franco MC, Stevens T, Bhatt A, Vargo JJ, Chahal P. Clinical outcomes of endoscopic management of pancreatic fluid collections in cirrhotics vs non-cirrhotics: A comparative study. World J Gastrointest Endosc 2019; 11(6): 403-412
URL: https://www.wjgnet.com/1948-5190/full/v11/i6/403.htm
DOI: https://dx.doi.org/10.4253/wjge.v11.i6.403