Age, socioeconomic features, and clinical factors predict receipt of endoscopic retrograde cholangiopancreatography in pancreatic cancer

Table 5 Analysis stratified by symptoms/conditions

	Adjusted OR of receiving ERCP (95%CI), amongst patients with Jaundice	Adjusted OR of receiving ERCP (95%CI), amongst patients with Cholangitis	Adjusted OR of receiving ERCP (95%CI), amongst patients with Pruritus
Sex
Male	1.00 (REF)	1.00 (REF)	1.00 (REF)
Female	1.17 (1.05-1.30)	0.99 (0.77-1.27)	1.00 (0.75-1.33)
Age
65-75	1.00 (REF)	1.00 (REF)	1.00 (REF)
76+	0.98 (0.88-1.09)	0.86 (0.67-1.10)	0.97 (0.73-1.29)
Marital status
Married	1.00 (REF)	1.00 (REF)	1.00 (REF)
Not married	0.85 (0.76-0.94)	0.97 (0.75-1.26)	0.94 (0.70-1.26)
Race
White	1.00 (REF)	1.00 (REF)	1.00 (REF)
Black	0.80 (0.67-0.95)	0.87 (0.58-1.28)	0.88 (0.52-1.51)
Other	0.73 (0.58-0.91)	0.64 (0.42-0.98)	1.00 (0.59-1.70)
Education (zip code)
> 50% high school only	1.00 (0.88-1.13)	0.79 (0.59-1.06)	1.23 (0.88-1.71)
> 50% some college	1.00 (REF)	1.00 (REF)	1.00 (REF)
Income (zip code)
< 75th percentile	1.13 (0.99-1.30)	1.50 (1.12-2.01)	0.84 (0.60-1.17)
> 75th percentile	1.00 (REF)	1.00 (REF)	1.00 (REF)
Year of diagnosis
2000-2003	1.00 (REF)	1.00 (REF)	1.00 (REF)
2004-2007	0.97 (0.86-1.10)	0.94 (0.70-1.26)	0.96 (0.67-1.39)
2008-2011	1.00 (0.88-1.13)	1.02 (0.76-1.37)	0.76 (0.54-1.06)
Metropolitan area
Metropolitan area	1.00 (REF)	1.00 (REF)	1.00 (REF)
Non-metropolitan area	0.79 (0.68-0.91)	1.30 (0.87 -1.95)	0.83 (0.56-1.24)
United States region
Southeast	1.00 (REF)	1.00 (REF)	1.00 (REF)
Northeast	0.94 (0.80-1.11)	1.23 (0.83-1.83)	0.73 (0.46-1.14)
Midwest	0.91 (0.76-1.07)	1.09 (0.71-1.69)	1.01 (0.61-1.67)
West Coast	0.95 (0.82-1.09)	1.02 (0.72-1.43)	0.75 (0.51-1.11)
Comorbid conditions
Charlson score 0	1.00 (REF)	1.00 (REF)	1.00 (REF)
Charlson score 1	1.06 (0.94-1.20)	1.24 (0.92-1.67)	1.24 (0.90-1.70)
Charlson score 2	0.93 (0.80-1.09)	0.69 (0.50-0.96)	0.77 (0.52-1.16)
Charlson score 3+	0.98 (0.83-1.16)	0.84 (0.58-1.21)	1.14 (0.72-1.80)
Cancer site
Body or tail	1.00 (REF)	1.00 (REF)	1.00 (REF)
Head of the pancreas	3.82 (3.23-4.50)	2.92 (1.98-4.31)	8.03 (5.57-11.56)
SEER historic stage
Localized	1.00 (REF)	1.00 (REF)	1.00 (REF)
Regional	0.85 (0.71-1.01)	0.79 (0.52-1.21)	1.21 (0.80-1.82)
Distant	0.51 (0.43-0.60)	0.44 (0.29-0.66)	0.83 (0.54-1.28)
Unstaged	0.75 (0.60-0.94)	0.46 (0.28-0.77)	0.88 (0.47-1.65)
Cancer directed therapies1
Chemotherapy	1.68 (1.48-1.90)	1.578 (1.20-2.07)	0.91 (0.66-1.26)
Radiation	1.21 (1.06-1.39)	1.25 (0.94-1.67)	1.19 (0.86-1.64)
Surgery	0.60 (0.52-0.69)	0.48 (0.35-0.67)	0.84 (0.5-1.20)

¹Referent category is not undergoing these treatments. OR: Odds ratio; CI: Confidence interval; Endoscopic retrograde cholangiopancreatography.