Severity of gastric mucosal atrophy affects the healing speed of post-endoscopic submucosal dissection ulcers

Table 4 Multivariate analysis of factors preventing healing of ulcers after endoscopic submucosal dissection

	Reduction rate over 90% at 4 wk		Reduction rate 100% at 8 wk
Variable	Not achieved (n = 45)	P value	Not achieved (n = 16)	P value
Gender (male vs female)	1.833 (0.715-4.698)	0.207	4.438 (1.253-15.724)	0.021
Helicobacter pylori	1.012 (0.463-2.213)	0.976	3.340 (0.866-12.885)	0.080
Atrophy (Kyoto A0+A1 vs Kyoto A2)	5.678 (1.190-27.085)	0.029	2.764 (0.309-24.711)	0.363
Tumor located in upper and middle third (vs lower third)	0.698 (0.283-1.724)	0.436	1.848 (0.493-6.933)	0.362
Mean procedure time (min)	1.007 (0.997-1.017)	0.194	0.998 (0.982-1.015)	0.850
Mean resected ulcer area (mm2)	1.000 (1.000-1.001)	0.443	1.001 (1.000-1.002)	0.023