Introduction of endoscopic submucosal dissection in the West

Table 1 Endoscopic mucosal resection vs endoscopic submucosal dissection for early Barrett’s and esophagogastric junction neoplasia

	ESD-6 Asian studies		EMR-10 Western studies		Odds ratio	P-value
Outcome	No. of studies	n (%)	No. of studies	n (%)	(95%CI)
Recurrence rate	6	1/333 (0.3)	5	10/380 (2.6)	8.55 (0.91, 80.0)	0.06
Perforation	6	5/335 (1.5)	9	8/686 (1.2)	1.07 (0.20, 5.62)	0.94
Delayed bleeding	6	7/335 (2.1)	9	8/686 (1.2)	0.46 (0.12, 1.75)	0.26
Stricture	5	7/207 (3.4)	7	3/456 (0.7)	0.21 (0.03, 1.41)	0.11
Method	No. of studies		Pooled procedure time (95%CI)
EMR	2		36.7 (34.5, 38.9)
ESD	5		83.3 (57.4, 109.2)

Modified from Komeda et al[7]. EMR: Endoscopic mucosal resection; ESD: Endoscopic submucosal dissection.