Characteristics of escape mutations from occult hepatitis B virus infected patients with hematological malignancies in South Egypt

Figure 2 Expression of hepatitis B virus DNA and antigens after transfection of Huh 7 cells with wild type hepatitis B virus genotype D clone (WT) and mutants with S gene mutations P120T (120T) and S143L (143L). A and B represent the extracellular expression of HBsAg and HBcrAg, respectively, by WT and S gene mutants (120T and 143L); C represents the intracellular expression of the core gene product (HBcrAg) by WT and S gene mutant clones; D: The density of the single-stranded DNA in Southern blot analysis of cell lysates of Huh7 cells transfected with WT and mutants with S gene mutations.