Meta-analysis reveals up-regulation of cholesterol processes in non-alcoholic and down-regulation in alcoholic fatty liver disease

Figure 1 A gene signature distinquishes alcoholic liver disease from non-alcoholic fatty liver disease. A: The heatmap shows a cluster analysis of logarithmic ratios of gene expression data from ALD liver biopsies vs control (blue bar) and NAFLD liver biopsies vs control (red bar); B: The table shows the 20 most up-regulated and 20 most-down-regulated genes from the signature indicating their log2-ratios and their P- and Q-values for the comparison ALD vs NAFLD. The full list of these genes can be found in Supplementary Table 2. ALD: Alcoholic liver disease; NAFLD: Non-alcoholic fatty liver disease.