Limitations and opportunities of non-invasive liver stiffness measurement in children

Figure 3 Real-time tissue elastography in a normal and cirrhotic liver. A: RTE with a normal strain histogram (mean: 113.3 a.u.; %AREA: 10%) in a 8-year-old female patient with cystic fibrosis and nearly normal liver structure; B: RTE with pathological strain histogram in a 6-year-old female patient with tyrosinemia type 1 and liver cirrhosis with small nodules. The mean value was 99.9, and the peak of histogram shifted to the left to lower values of the mean. The percentage of stiffer areas (colour-coded in blue; %AREA) increased up to 23.6%. This histogram is more flattened in comparison to the normal strain histogram. RTE: Real-time tissue elastography.